In addition, MYO7A (MIM 276903; 11q13.5) variants may be inherited in an AD manner, while digenic inheritance for PCDH15 (MIM 605514; 10q21.1) and CDH23 (MIM 605516; 10q22.1) were demonstrated in mice and humans [73]. This evidence concerns the gene PCDH15 and Alzheimer disease.