TCOF1 and Treacher-Collins syndrome: We previously ruled out a heterozygous variant in TCOF1 (MIM 606847; 5q32-q33) due to lack of clinically diagnosed craniofacial hallmarks of AD Treacher-Collins syndrome (MIM 154500), but upon review, we cannot rule out that the TCOF1 variant also contributes to hearing loss and temporal bone anomalies, as was previously described (Table S1) [70].