Although the evidence is continuously growing that the commonly used but rather nonspecific interleukin (IL)-6, C-reactive protein (CRP) and D-dimer levels are significantly elevated and linked to poor outcomes in most cases, robust biomarkers for the early risk stratification and clinical management of COVID-19 patients are still lacking, however, they are urgently needed [5,6,7]. This evidence concerns the gene CRP and COVID-19.