A recent study investigated taraxasterol (Figure 6), a pentacyclic-triterpene derived from taraxastane (mevalonate pathway), found in Taraxacum officinale of Chinese origin, in IL-1β-stimulated (10 ng/mL) human RA-FLS in vitro as well in a CIA model in mice (CIA was induced by two immunizations in mice (secondary immunization was given 12 days after the primary immunization)). This evidence concerns the gene IL1B and rheumatoid arthritis.