The reanalysis of T-cell scRNA-seq datasets in NSCLC [44] and CRC [65] highlighted a higher CCR4 gene expression mainly in Tregs in peripheral blood mononuclear cells (PBMC), whereas, in the TME, the CCR4 gene is highly expressed in TA-Tregs but, also, upregulated on other T-cell subsets (Figure 2). The gene discussed is CCR4; the disease is non-small cell lung carcinoma.