Consistently with the increased proportion of MDMs expressing M1 markers, we observed that the co-culture of murlentamab-opsonized SKOV3-R2+ tumor cells with both M0 and TAM-like MDMs induced a significant increase in IL1β, IL6 and IFNγ pro-inflammatory cytokine production (Figure 3B). The gene discussed is IL6; the disease is neoplasm.