Genotype combination analysis of GSTM1 rs1056806 (C/T), SOD2 rs4880 (A/G), SOD3 rs2536512 (A/G), and GPX1 rs1800668 (A/G) revealed four common combinations with higher risk of obesity; CGAG (OR = 6.15, 95%CI = 1.46–25.8, p = 0.014), CAAA (OR = 5.0, 95%CI = 1.23–20.3, p = 0.025), TGGG (OR = 3.25, 95%CI = 1.06–9.95, p = 0.040), and CGAG (OR = 2.95, 95%CI = 1.27–6.86, p = 0.012) (Table 3). Here, GPX1 is linked to obesity due to melanocortin 4 receptor deficiency.