Being a multifunctional scaffold protein, p62 serves as a signalling hub by interacting with the core molecules involved in a variety of important cell life activities [42,43], An increasing number of studies have proved that the integrated analysis of the expression of p62 and other key proteins in signalling pathways can be used as a biomarker for cancer prognosis [44,45], especially including ovarian cancer [2,46]. This evidence concerns the gene SQSTM1 and cancer.