This is in agreement with previous bibliographic data showing decreased decorin protein expression in human CAFs treated with SKBR3- and MDA-MB-231-derived secretomes [97] and decreased decorin production in human LX2 stellate cells upon exposure to the conditioned media of different hepatoma cell lines (Hep3B, HLE, HepG2, and HuH7) [111]. The gene discussed is DCN; the disease is hepatocellular carcinoma.