STING1 and Hepatitis: Activation of STING was associated with an aggravated expression of several inflammatory cytokines, including IL-18, IL-6, IL-1β, TNFα, and C-X-C motif chemokine ligand 10 (CXCL-10) in HFD-induced NAFLD mice, whereas repressing STING signaling attenuated lipid accumulation and liver inflammation [86].