Clinicopathologic analysis revealed that high SNHG15 expression was associated with tumor differentiation, lymph node metastasis and tumor stage (p < 0.005), and patients with high SNHG15 expression had a shorter OS compared with the low SNHG15 expression group (p = 0.003). The gene discussed is SNHG15; the disease is metastatic malignant neoplasm in the lymph nodes.