AKT1 and cancer: As illustrated in Figure 1C, the biological functions of these miRNA candidates were significantly involved in cancer-related signaling pathways, including those of proteoglycans in cancer, MAPK, TGF-beta, FoxO, colorectal cancer, cellular senescence, the adherens junction, PI3K-Akt, Hippo, autophagy, focal adhesion, and ErbB.