A study performed on several types of cells (MM.1 S, MM.1 R, and U266) demonstrated that the effects of PINK1-dependent mitophagy on MM onset are regulated by the stimulation of the MPS 1 binder kinase activator (MOB1) B-mediated Hippo pathway and the successive reduction in YAP/TAZ expression [132]. This evidence concerns the gene WWTR1 and Miyoshi myopathy.