AKT1 and cancer: Previous studies have demonstrated that ampelopsin inhibits proliferation, promotes apoptosis, and suppresses the invasion and migration of several cancer cells, including hepatocellular carcinoma, non-small cell lung cancer, osteosarcoma, ovarian cancer, gastric cancer, breast cancer, melanoma, and glioma, by regulating the mitogen-activated protein kinase (MAPK), AMP-activated protein kinase (AMPK), and PI3K/AKT pathways [27,28,29,30,31,32,33,34].