In placental bed samples, significant changes in the ratio of miRNA and its potential target genes expression levels were revealed and were unique for IUGR (miR-30c-5p/VIM, miR-28-3p/VIM, miR-1-3p/ANXA2, miR-30c-5p/FBN1; miR-15b-5p/MYL6), unique for PE (miR-185-3p/FLNA), and common for IUGR and PE (miR-30c-5p/YWHAZ and miR-654-3p/FGA). This evidence concerns the gene FBN1 and fetal growth restriction.