In contrast, a significant increase in the miR-1-3p/ANXA2 expression level ratio due to an increase in miR-1-3p expression and a decrease in annexin A2 expression in the placental bed in the group of women with IUGR < 32 can reflect microvascular fibrin accumulation and, as a result, increased thrombogenesis, necessitating immediate pregnancy termination. This evidence concerns the gene ANXA2 and fetal growth restriction.