Thus, a significant decrease in the miR-1-3p/ANXA2 expression level ratio due to a decrease in miR-1-3p expression and an increase in ANXA2 expression in the placental bed in the group of women with IUGR > 34 can be a compensatory mechanism to prevent increased thrombogenesis, as well as a consequence of hypoxia caused by insufficient placental perfusion. Here, ANXA2 is linked to fetal growth restriction.