FN1 and fetal growth restriction: However, according to the previous reports, specific changes in fibronectin isoform expressions are dependent on the stage of villous maturation and extravillous trophoblast cells invasiveness [71,72], and placental fibronectin appeared to be unaffected in women with late-onset IUGR and SGA fetuses in contrast to early-onset pre-eclampsia with statistically increased level [73].