Evaluating the effectiveness of transplantation can lay the foundation for the development of new treatments for these diseases, including retinitis pigmentosa with RPE-related gene abnormalities (such as RPE65, RDH5, and MERTK) [13,44,45,46,47,48,49,50,51], AMD with RPE atrophy [52,53,54,55,56]. This evidence concerns the gene RPE65 and age-related macular degeneration.