RhoH/TTF gene was initially discovered as a translocation partner of LAZ3/BCL6 gene in a non-Hodgkin’s lymphoma cell line, VAL t (3;4) (q27;p23), and within the IgH gene, t (4;14) (p13;p32), in patients with multiple melanoma [38]. This evidence concerns the gene BCL6 and Hodgkins lymphoma.