EMD and dilated cardiomyopathy: Compared to EDMD2, the X-linked Emery–Dreifuss muscular dystrophy (EDMD1) caused by mutations in EMD gene, encoding for emerin [106], displays muscle weakness with humero-peroneal distribution of weakness, contractures as the presenting symptoms, less common loss of walking ability and lower risk of dilated cardiomyopathy and sustained ventricular tachyarrhythmia [46,105,107].