Some data support the hypothesis that also Mitochondrial Inner Membrane Magnesium Transporter (MRS2), Magnesium Transporter Protein 1 (MAGT1), Solute carrier family 41 member 1 (SLC41A1), Metal Transporters CNNM1 and CNNM4 may be dysregulated in colon cancer [36,38]; however, more studies are necessary to confirm these observations. This evidence concerns the gene MRS2 and colonic neoplasm.