Platelets are able to increase the expression of tissue factor (TF) on tumour cells, therefore enabling tumour cells to activate the coagulation cascade, which, in turn, maintains an activated state in platelets that facilitates thrombosis [8,9,10,11] and ensures a steady supply of growth factors needed for tumour progression through platelet signalling [12,13,14]. The gene discussed is F3; the disease is neoplasm.