CD80 and cancer: According to the dataset of The Cancer Genome Atlas (TCGA) PanCancer Atlas Studies, available at the cBioPortal (https://bit.ly/3hE21OQ, accesse on 5 March 2021; 10,953 cancer patients from 32 studies), the CD80 gene is altered in 2% of patients, including amplifications, deletions, and mutations that may result in unfunctional CD80.