Our previous analysis of the histological findings of finger lesions from 74 DM patients characterized according to myositis-specific autoantibodies (anti-MDA5, anti-TIF1γ, and anti-ARS) indicated that eczematous reactions (spongiosis) and psoriasiform dermatitis (psoriasiform acanthosis and parakeratosis) were significantly more frequently observed in skin samples of anti-ARS antibody-positive patients than in anti-MDA5 or TIFγ antibody-positive patients [41]. This evidence concerns the gene IFIH1 and dermatomyositis.