The anti-MDA5 antibody, which was termed an anti-CADM-140 antibody that reacts with a 140-kDa cytoplasmic protein [14], has been reported to present a high specificity for clinically amyopathic DM (CADM) accompanied by rapidly progressive ILD (RP-ILD) [15]. Here, IFIH1 is linked to clinically amyopathic dermatomyositis.