A study by Pang et al. (2017) showed that TQ (3, 10 μM) suppressed cancer growth in THP-1 and MV4-11 leukemia cell lines by reducing the activity of DNA-methyltransferase 1 (DNMT1), As such, it decreased the total DNA methylation in two ways; downregulating DNMT1 and competing with co-factor SAM/SAH to inactivate DNMT1. The gene discussed is DNMT1; the disease is leukemia.