In a recent in vitro model, the interaction between DCs-MM and T lymphocytes led DCs to secrete IL-6 and the immunosuppressive enzyme indoleamine 2,3 dioxygenase (IDO), resulting in the anergy of activated T cells and the differentiation of T cells into suppressive CD25 high/FOXP3+/CD4+ Treg [178]. This evidence concerns the gene IL6 and Miyoshi myopathy.