Antiphospholipid syndrome (APS) is an autoimmune disease characterized by the production of β2-glycoprotein I (β2GPI)-dependent antiphopholipid autoantibodies (like APL, including lupus anticoagulant, anticardiolipin antibody, anti-β2GPI antibody), arterial/venous thrombosis or obstetrical complications [1]. The gene discussed is APOH; the disease is antiphospholipid syndrome.