APOH and autoimmune polyendocrinopathy: Table 1 shows the findings: 5 mg/kg crassolide produced less severe APS manifestations as follows: prolonged aPTT, decreased platelet count, anti-β2GPI antibody, increased percentage of fetal loss, and decreased mesenteric venule occlusion time. In particular, the mesenteric venule occlusion time was prolonged by ~2 fold (858 ± 493 s) when compared with controls (538 ± 202 s) (Figure 7a,b).