The important functions of elastic fiber networks, consisting predominantly of elastin (ELN) and fibrillin, are very obvious, and they are underlined by the fact that mutations in the ELN gene are the cause of several syndromes: Williams–Beuren syndrome, supravalvular aortic stenosis, and cutis laxa-autosomal dominant 1 [74,75,76,77]. Here, ELN is linked to autosomal dominant cutis laxa.