U2AF1 and myelodysplastic syndrome: Mutated SF3B1, along with mutated U2AF1, Serine and Arginine Rich Splicing Factor 2 (SRSF2) and Zinc Finger CCCH-Type, RNA Binding Motif And Serine/Arginine Rich 2 (ZRSR2) genes, is also very frequently observed in MDS [36] and has been linked to poor survival rate [34].