SOST and Hypertension: This model revealed intima-media thickness (multiple R = 0.675, p < 0.0001), serum sclerostin (R = 0.727, p = 0.020), and left ventricular end-diastolic diameter (R = 0.763, p = 0.035) as determinants of PWV when the model was adjusted for hypertension (Table 3B).