SPP1 and colitis: After 7 days of colitis induction, the expression of 18 genes, namely Il1a, Il1b, Il3, Il4, Il11, Il17a, Il17f, Il1r1 Il1rn, Il2rb, Il10ra, Faslg, Ifng, Mif, Osm, Pf4, Spp1, and Tnfsf4, was up-regulated whereas the expression of the Bmp2, Cd40lg, Lta, and Tnfsf11 genes was down-regulated in the CβG- group as compared to that in the HβG- control group.