Furthermore, the expression of identified intercellular cell adhesion molecule (ICAM)-1 with a sustained surface expression and platelet-derived growth factor (PDGF)-B with a transiently-induced production by phorbol myristate acetate (PMA)-treated THP-1 derivatives was analyzed in the lesional skin of a Blau syndrome patient by immunostaining. The gene discussed is PDGFB; the disease is Blau syndrome.