Validated genetic loci for BC risk include 8p22 (NAT2, GSTM1), 8q24.21 (MYC), 3q28 (TP63), 8q24.3 (PSCA), 5p15.33 (CLPTM1L-TERT), 4p16.3 (TACC3-FGFR3), 22q13.1 (APOBEC3A-CBX6), 19q12 (CCNE1) and 2q37.1 (UGT1A) [34]. The gene discussed is NAT2; the disease is breast cancer.