Gene expression levels of multiple typical inflammatory cytokines confirmed that, after 8 weeks of diabetes, the NTN4KO retinas had an overall higher mRNA expression of Icam1 (Figure 2E), Ccl2 (Figure 2F), and Il6 (Figure 2G) compared to non-diabetic NTN4KO, and also when compared to their diabetic NTN4WT counterparts in the case of Ccl2 (Figure 2F), Il6 (Figure 2G) and Il1b (Figure 2H) expression. Here, IL6 is linked to diabetes mellitus.