KRAS and Familial adenomatous polyposis: Considering all the samples analyzed (including normal mucosa) in this study from FAP patients and the single patient with MAP, the authors found that potential driver alterations in TTN, SMAD4, GNAS, ASXL1, KRAS, FAT4, ZFHX3, FBXW7, PTPRT, and SOX9 genes occur with a frequency of between 37% and 16% (Table 1).