INS and cardiovascular disorder: Findings of the study [214] revealed that alternate-day fasting and the daily calorie restriction resulted in a similar weigh loss at month 6 (−6.8% vs. −6.8%) and at month 12 (−6.0% vs. −5.3%), and that the risk factors for cardiovascular disease including blood pressure, heart rate, triglycerides, fasting glucose, fasting insulin, insulin resistance, C-reactive protein, and homocysteine concentrations at month 6 and 12 were similar in the intervention groups.