A 12-week cycle ergometer program performed at 65–75% of maximal oxygen consumption (V̇O2max) was shown to influence peripheral tissue insulin sensitivity, visceral adiposity, skeletal muscle protein content of glucose transporter type 4 (GLUT4), and total protein kinase B in both PCa patients undergoing ADT and non-exercise groups [15]. Here, INS is linked to posterior cortical atrophy.