PRNP and Creutzfeldt Jacob disease: It is worth noting that the migration of the top PrP band corresponding to the FL-PrP in sCJD or non-CJD was slightly slower than that of the top PrP band in VPSPr, but the difference was much smaller than that found in glycosylated PrP (Figure 5C,D vs. Figure 5A,B).