For instance, vitamin D has been recently shown to recover expression levels of IL-33 in ARPE-19 cells after H2O2 addition, which stimulated expression of antioxidant genes [35], suggesting a key role of this cytokine in AMD since it was also shown to inhibit murine CNV [90] and to reduce retinal inflammation [91]. The gene discussed is IL33; the disease is age-related macular degeneration.