CASP1 and adult-onset Still disease: On the contrast, significantly higher levels of caspase-1 and IL-18 were noticed in AOSD patients carrying the CC genotype (median, 121.3 pg/mL, IQR: 72.6–251.7 pg/mL; and 1748.6 pg/mL, IQR: 492.6–12,433.9 pg/mL; respectively) compared with the carriers of CT/TT genotype (median, 72.6 pg/mL, IQR: 42.0–108.7 pg/mL, p = 0.019; and median, 609.3 pg/mL, IQR: 392.8–1550.6 pg/mL, p = 0.046; respectively) (Figure 2B,D).