There are also several genes that carry mutations in only one or two of the nine regions within the same tumor, such as ARID2, BAD, BCL2, BRAF, CBL, CDKN2B, FBXW7, KMT2D, MDM2, MET, MYC, PIK3CA, PTEN, SF3B1, SOX2, TERT and TP53 (Figure 3D). The gene discussed is SOX2; the disease is neoplasm.