MDM2 and neoplasm: In addition, there are also several genes that carry mutations in only one or two of the nine regions of the same tumor (ARID2, BAD, BCL2, BRAF, CBL, CDKN2B, FBXW7, KMT2D, MDM2, MET, MYC, PIK3CA, PTEN, SF3B1, SOX2, TERT and TP53).