ALK and tuberculosis: Notably, some gene amplifications (such as MET, RET and ALK amplifications) or rearrangements [such as ALK, ROS1, Proto-Oncogene Tyrosine-Protein Kinase Receptor Ret (RET), NTRK, and Neuregulin 1 (NRG1) rearrangements] are less frequently detectable in a LB that in a TB.