Table S1 reports patients characteristics. SelectMDx was positive in 144 (46.5%) cases and a PI-RADS score 4–5 in 78 (25.2%) cases. A concordance between SelectMDx and mpMRI was found in 63.3% of cases. Out of 104 PCa (33.5%) detected at biopsy, 62 (20.0%) were csPCa. Table 1 reports stratification of subjects according to pathologic results at biopsy (i.e., PCa negative, all PCa, and csPCa). There was a significantly difference between PSA levels between the groups (p < 0.0001, and p = 0.001) (Table 1 and Figure S1a). This evidence concerns the gene KLK3 and posterior cortical atrophy.