CX3CR1 and precursor B-cell acute lymphoblastic leukemia: In line with their findings, our group confirmed the increase in NC CD14dimCD16+ monocytes in the PB of B-ALL patients at diagnosis, compared to controls, and highlighted that they express low levels of the CCL2 receptor CCR2, but very high levels of the Fractalkine (CX3CL1) receptor CX3CR1 [70], as previously shown for this monocyte subset under physiological conditions [112].