Combined AXL inhibition and PD-1 blockade was shown to mount a potent synergistic antitumor efficacy, leading to tumor eradication in ovarian cancer murine models by inducing the expression of T cell-recruiting chemokines (e.g., CXCL9, CXCL10, and CXCL11), while decreasing the expression of chemokines related to suppressive cell recruitment (e.g., CCL2, CCL3, and CCL4). This evidence concerns the gene CCL4 and neoplasm.