We have found no studies evaluating the association of ITGA4 polymorphisms with natalizumab response; however, a study of 117 Caucasian patients in Slovakia found an association between the AG genotype of the rs1143676 polymorphism (G>A, Gln878Arg) and susceptibility to MS (OR = 1.73; 95% CI = 1.07–2.81; p = 0.024) [56]. The gene discussed is ITGA4; the disease is myeloid sarcoma.