Dendritic cells loaded with TEXs in tumor-draining lymph nodes could promote the production of pro-inflammatory cytokines, then the level of IL-6, IFN-γ and IL-12 in the tumor microenvironment would become high, while the IL-10 was of a low level, which promoted the anti-tumor response of Th1 [6]. This evidence concerns the gene IL6 and neoplasm.