APP and neurodegenerative disease: Further, HuD regulates the expression of mRNAs involved in the pathogenesis of neurodegenerative diseases or cancer, including amyloid precursor protein (APP), β–site APP–cleaving enzyme 1 (BACE1), lncRNA BACE1AS [76], neprilysin (NEP) [77], tau [78,79], superoxide dismutase 1 (SOD1) [80], and MYCN [81,82].