Results of this study demonstrated that FPR1 is positively modulated by resveratrol treatment in the striatum and hippocampus in a similar manner, and that this upregulation is detectable in a picture of neuroinflammation reduction, thus suggesting a possible protective action for FPR1 in neurodegenerative diseases like PD and AD, in which the inflammation role in both pathogenesis and progression have been established. The gene discussed is FPR1; the disease is Alzheimer disease.