TGFB1 and cystic fibrosis: CF stimulate the initial breakdown of the ECM, resulting in activation and release of profibrotic signalling molecules, such as transforming growth factor β (TGF-β), and some extracellular damage-associated molecular patterns (DAMPs), such as SLRPs, syndecans, glypicans and hyaluronic synthases [14,15,16,17,18].