CCL3 and neoplasm: In earlier studies of the potential impact of activated mast cells on tumor growth Oldford et al., 2010 [33] showed that mast cells exposed to the TLR2 agonist, Pam3CSK4, facilitate the recruitment of CD3+ T cells in addition to NK1.1+ NK cells to B16-F10 lesions in a CCL3-dependent manner.