On the other hand, a previous study conducted by Sozen highlighted that the myometrium of the women with uterine fibroids taking GnRHa and in particular the endothelial cells of blood vessels in myometrial tissues surrounding the leiomyoma show higher MCP-1 levels than the myometrium of the women with uterine fibroids not taking GnRHa [145]. The gene discussed is CCL2; the disease is leiomyoma.