Two reports demonstrated the establishment of sialidosis-iPSC models with NEU1 mutations c.649G > A/644 T > C, c.1109A > G/c.1109A > G [43], c.1195_1200dup/c.679G > A [23,32], or c.544 A > G transition and 667–679 deletion from sialidosis patient fibroblasts [21]. The gene discussed is NEU1; the disease is sialidosis.