NEU1 and sialidosis: Similarly to sialidosis-NPCs carrying NEU1D176G or NEU1P316S [21], our sialidosis-iNPC models carrying NEU1G227R or NEU1V275A/R347Q mutations revealed correlations of NEU1 mutations with sialidosis-specific molecular defects and disease phenotypes, which are specifically associated with abnormal lysosomal dynamics.